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Estriol

Estriol
Estriol
Product Code : 50-27-1
Brand Name : EP 8.0
Product Description

We have carved a reputed niche in the industry for manufacturing and supplying Estriol. It is a steroid which is considered as weak estrogen and is the major urinary estrogen. This compound is produced in high amounts by placenta during pregnancy. It has chemical formula C18H24O3 and molar mass of 288.387 g/mol. Estriol is also utilized for giving hormone therapy for providing relief from menopause symptoms. It gets metabolized by glucuronidation & sulfation.

Features:

 

  • It is a hydroxylated metabolite of estradiol

  • Possesses benefits for bone density, multiple sclerosis, & cardiovascular health

  • Can donate and accept 3 hydrogen bonds

 

 

 

Technical Specifications:

Test items

In-house Standard

Analytical method

Description

White or almost white crystalline  powder

Visual  

Solubility

Practically insoluble in water, sparingly soluble in ethanol (96% per cent)

Visual  

Identification

IR:  Meets the requirements

TLC:  Meets the requirements

IR

TLC

Specific Rotation

+60°~+64°

EP8.0

Loss on drying

≤ 0.5%

EP8.0

Particle Size

≤30μm

Particle Size Analyzer

Related substances

Impurity A (RRT≈1.1)

Impurity B (RRT≈0.4)

Impurity C (RRT≈0.47)

Impurity D (RRT≈0.5)

Impurity E (RRT≈0.7)

Impurity F (RRT≈0.75)

Impurity G (RRT≈1.2)

Unspecified impurity

Sum of impurity other than A

 

≤ 0.5%

≤ 0.5%

≤ 0.5%

≤ 0.5%

≤ 0.5%

≤ 0.5%

≤ 0.5%

≤ 0.1%

≤ 1.0%

HPLC

 

 


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